Openbookopenbook
Openbook
SBIO
+10.70 · +26.34%
$51.33 · NYSE ARCA

ALPS Medical Breakthroughs ETF (SBIO) ETF Analysis | Health

ALPS · United States
AUM:$138.0M
#– of – in Health ETFs

Educational tool only – Figures are based on historical data, holdings and expense metrics for informational purposes. This is not financial advice or a recommendation to buy or sell any security. Always conduct your own research or consult a qualified financial adviser.

Market Performance

Up 64.6% over the past year, reflecting strong price momentum.

Cost Efficiency

Ongoing charge of 0.50% — moderate cost. Consider how fees compound over long holding periods.

What is SBIO?

The fund employs a passive management - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index.

Performance Highlights

Returns (%)
Top Sectors (%)

Investment Breakdown

Strong Recent Performance
SBIO delivered 64.6% over the past year. Historical returns only — past performance is not indicative of future results.
Moderate Cost
Expense ratio of 0.50%. Consider how fees compound over a long holding period.
Moderate Concentration
Top 10 holdings make up 30.8% of the ETF — a moderate level of name concentration.
ETF Information
AUM$138.0M
Expense Ratio0.50%
Dividend Yield0.00%
Holdings49
Inception DateDec 2014
DomicileUnited States
DistributionNA
Index–
ProviderALPS
Beta1.38
CategoryHealth
CurrencyUSD
Portfolio Impact

How would SBIO affect your portfolio?

Sign in to see exactly what adding this ETF changes — sector exposure, yield, diversification, volatility. Real numbers from your actual holdings.

Sign in
Example preview
6168
+7 points · better diversified

Chart Tools

My Portfolio

Sign in to overlay your portfolio on the chart.

Sign in
Compare Equity
Uses ISF.L (iShares FTSE 100 ETF)
Indicators

Performance Metrics

Historical returns

6M
+30.1%
1Y
+90.8%
3Y
+135.0%
5Y
+49.2%
OpenBook InsightIf you had invested £10,000 in SBIO 5 years ago, it would have grown to £14,924 — a gain of £4,924.

Annual Returns

Calendar year performance

SBIO delivered positive returns in 4 of the last 5 calendar years.
YearSBIO
2026 YTD+33.8%
2025+53.7%
2024+4.3%
2023+11.0%
2022-30.2%
CAGR 4yr+5.6%
4/5 positive yearsAvg return: +14.5%Worst year: -30.2% (2022)

Technical Analysis Summary

Automated insights from historical price action and indicators

Technical Regime: MIXED
Trend Strength
67%
Positive
Volatility
27.4%
Moderate
Momentum
+5.5%
30-day change
Support Level
63.53
Key floor
Key Insights
  • Monitor key support and resistance levels as part of broader risk assessment.
openbook

Stock research for UK and US investors. Make smarter decisions, faster.

Questions? Email us at contact@openbookanalytics.com

© 2026 Openbook Analytics Ltd · Company No. SC843579 · Registered in Scotland

256-bit encryption GDPR compliant UK data centres

Openbook Analytics Ltd (Company No. SC843579) is registered in Scotland. Registered office: Strathclyde Inspire Hub, University of Strathclyde, Graham Hills Building (Level 6), 50 Richmond Street, Glasgow, G1 1XP. Openbook Analytics is not authorised or regulated by the Financial Conduct Authority (FCA). The content on this platform is provided for general informational and educational purposes only and does not constitute financial advice, investment advice, trading advice, or any other form of advice. You should not treat any content on this platform as a recommendation to buy, sell, or hold any financial instrument. Past performance is not a reliable indicator of future results. The value of investments and the income from them can go down as well as up, and you may get back less than you invest. User-generated content, including community posts and commentary, reflects the personal opinions of individual users, is not verified for accuracy, and does not represent the views of Openbook Analytics Ltd. You should always conduct your own research or consult a qualified, FCA-regulated financial adviser before making investment decisions. Data displayed on this platform may be delayed or inaccurate and is provided "as is" without warranty. Openbook Analytics Ltd accepts no liability for any loss arising from reliance on the information provided.