Spyre Therapeutics Inc.(SYRE)
USD --+0.00%
Reward35Moderate
Risk56Medium-High
📊75%Data
SYRE
+0.0 · +0.00%
USD · NASDAQ
Spyre Therapeutics Inc. | Healthcare
Capital Destroyer
Market Cap:3.38Bn
ℹ️
Reward Rating
35
Moderate
Bottom 5% (model universe)
75% data coverage
ℹ️
Risk Rating
56
Medium-High
Risk Assessment
ℹ️

Educational tool only – Scores are based on historical data and financial metrics for informational purposes. This is not financial advice or a recommendation to buy or sell any security. Always conduct your own research or consult a qualified financial adviser.

ℹ️ Educational tool only · More
Limited data coverage
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Market Performance

Stock returned +10.0% over the past year, broadly in line with market conditions.

Analyst Target

Analyst consensus price target: $58.57.

What is Spyre Therapeutics Inc.?

, a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD) and rheumatic diseases.

SYRE · Verdict

Limited reward · elevated risk

SYRE's standout is balance sheet; cash flow and volatility weigh on the picture.

Based on 88% data coverage

SYRE · Verdict

What’s working & what to watch

Strengths 1

  • Balance sheet100/100

    Current ratio 13.25

Watchouts 4

  • Cash flow5/100

    Weak vs peers

  • Volatility5/100

    Weak vs peers

  • Profitability10/100

    -25% return on equity

  • Growth31/100

    Earnings +22.8% CAGR

Model-based scoring. For information only — not financial advice.

What is Spyre Therapeutics Inc.?

, a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD) and rheumatic diseases. The company develops SPY001, a humanized monoclonal immunoglobulin G1 antibody that is in phase-2 clinical stage designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease); and SPY002 and SPY072 " anti-TL1A mAbs designed to bind to tumor necrosis factor-like ligand 1A (TL1A). The company is listed on the NASDAQ in USA, operating in the Healthcare sector, with a market capitalisation of 3.38B.

Financial Highlights

Investment Breakdown

📈 Growth
Moderate growth momentum — positive trajectory without breakout acceleration.
💰 Profitability
Thin or inconsistent margins weigh on earnings quality.
⚠️ Risk
Moderate volatility with meaningful macro and earnings sensitivity.
💸 Valuation
Valuation is less clear with a negative earnings base.

OpenBook Logo Analysis

Reward: Moderate (35)

The scoring profile indicates weak reward characteristics across most factors, including valuation and momentum. Risk indicators are elevated — volatility and macro sensitivity warrant consideration.

For informational purposes only. Not financial advice.

Company Information
SectorHealthcare
Market Cap3.38B
P/E RatioN/A
Dividend YieldN/A
52 Week High45.76
52 Week Low10.91
Last AnnualDecember
IPO Date4/7/2016
IncorporatedUSA
Shares Outstanding79M
No. of Employees102
IndustryBiotechnology
ExchangeNASDAQ
Beta3.161
CurrencyUSD